Democratic nominees have won the White House in every cycle since the formation of the Republican Party in which they carried at least half of the region’s states.
Less than 10 failed U.S. Senate nominees in the direct election era were later rewarded with an appointment to a senate seat.
Only three other governors have made more than one appointment to the chamber during the last 64 years.
Each of the Top 5 and eight of the Top 10 states which have most frequently elected U.S. Senators from a party other than the sitting president are located in the Midwest; five host contests in 2018.
Over the last 50 years, 41 losing nominees in special elections landed a rematch in the subsequent general election – only six were victorious and just two since 1981.
The 12-state region will see its collective delegation decrease in size for the 10th consecutive decade, although at its lowest rate in a half-century.
Only three presidential candidates have attempted a third major party bid after two failed attempts in the modern primary era.
Only five of 55 U.S. Senate partisan winning streaks of eight in a row have been halted in the subsequent contest during direct election era.
Mandel vs. Brown will be just the second U.S. Senate rematch in Ohio history; Mandel seeks to become the fifth failed nominee to come back and win a seat.
Only one of the 73 Republican U.S. House members from Trump states with Democratic US Senators on the 2018 ballot has mounted a challenge.