Democrats and Republicans in six states have still never nominated a woman to its top executive office.
Over the last 170+ years, each of the last 15 times a U.S. House Speaker retired, resigned, or died in office, his party held the seat.
Each of the Top 5 and eight of the Top 10 states which have most frequently elected U.S. Senators from a party other than the sitting president are located in the Midwest; five host contests in 2018.
Democrats have to defend plenty more competitive seats this cycle, but a bad November for Republicans could write them into the history books.